Fig. 5

Expression of lipoxygenase 12 and 15 in MS patients and lipoxygenase 12/15 in EAE mice. A–D Graphs showing the mRNA levels of ALOX12 A, C and ALOX15 B, D in PBMCs of MS individuals (n = 11) and healthy donors (n = 8) B, C and in MS brain AL and NAWM C, D (n = 9). E Time course expression of Alox12/15 mRNA levels in the spinal cord of EAE mice over disease progression (n = 3–4 per time point). Unpaired t-test in A–D and one-way ANOVA, Bonferroni’s post hoc test in (E). Data are shown as mean ± SEM