Fig. 1

Lack of CD36 diminishes accumulation of myeloid cells in the ipsilateral cortex of neonatal mice subjected to tMCAO. A Gating strategy to identify subsets of myeloid cells from the dissociated cortices by flow cytometry. B–E Quantification of CD45^hiCD11b⁺ myeloid cells (B), CD45^hiCD11b⁺Ly6c^hi inflammatory monocytes (C), CD45^hi11b⁺Ly6c^intLy6g⁺ neutrophils (D), and CD45^hi11b⁺Ly6c^intLy6g⁻ patrolling monocytes (E) ipsilateral (Ipsi) and contralateral (Contra) to tMCAO in WT and CD36 KO mice at 3 h and 13 h reperfusion. Two-way ANOVA with post-hoc Tukey’s Multiple Comparison test was performed to compare groups with multiple independent variables. Dots represent individual mice. Data are shown as mean ± SD. In this and the following figures 3 h/3 h refers to 3 h MCAO followed by 3 h reperfusion. 3 h/13 h refers to 3 h MCAO followed by 13 h reperfusion. Individual p values are listed within figures for data that are significant