Fig. 6

Lack of CD36 reduces expression of key genes in Granulocyte Adhesion and Diapedesis pathway in pups subjected to tMCAO followed by 3 h reperfusion. IPA showing the molecular pathway of Granulocyte Adhesion and Diapedesis overlayed with differential expression data of WT (A) and CD36 KO (B) in the CP ipsilateral to MCAO, showing lower expression of IL-1, P-selectin and E-selectin, LFA1 and MAC1 in CD36 KO CP. The red indicates gene’s upregulation and green represents downregulation