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Fig.8 | Journal of Neuroinflammation

Fig.8

From: Fluoxetine inhibited the activation of A1 reactive astrocyte in a mouse model of major depressive disorder through astrocytic 5-HT2BR/β-arrestin2 pathway

Fig.8

Schematic diagram showing inhibitory effects of fluoxetine on of A1 astrocyte reactivity in depression. Fluoxetine (FLX) administration inhibits the activation of A1 astrocytes in CMS mice and primary astrocytes via 5-HT2BR/β-arrestin2 pathway not Gq protein pathway in astrocytes, which could improve behavioral impairments of CMS mice

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Journal of Neuroinflammation

ISSN: 1742-2094