Fig. 2

Treatment with 24A improved the ability of GCI/R mice to explore novel objects. A–C Schematic diagrams of the novel object recognition test. D, E Discrimination index (n = 12, one-way ANOVA, p = 0.002) and time ratio (n = 12, one-way ANOVA, p = 0.010) in the ORT at 24 h. (Discrimination index = time spent exploring the novel object/total time spent exploring the familiar and novel objects), (time ratio = time spent exploring the novel object/total time spent exploring familiar and novel objects). F, G Total exploration frequencies (n = 12, one-way ANOVA, p = 0.159) and total exploration time (n = 12, one-way ANOVA, p = 0.076) in the ORT at 24 h. H Representative trajectory diagram in the ORT at 24 h. (**p < 0.01, *p < 0.05, ns indicates no significant differences)