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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

Fig. 5

Lateral ventricle administration of BMSC-exos inhibited the proliferation and activation of microglia in the hippocampus of mice injected with STZ. A Fluorescence detection of microglia marker IBA1 in hippocampus B Quantification of the number of IBA1 positive cells. C Microglia in different states (left: resting state; right: activated state); D The ratio of activated microglia to the total number of microglia. Data are presented as means ± SEM, with n = 3 in each group (*P < 0.05, **P < 0.01)

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