Fig. 6

Lateral ventricle administration of BMSC-exos inhibited the activation of astrocytes in the hippocampus of mice injected with STZ. A Fluorescence detection of GFAP, a marker of activated astrocytes in hippocampus; B Quantification of the number of GFAP-positive cells. C Western Blot photos of IBA1 and GFAP; D IBA1 and GFAP protein expression levels quantification. Data are presented as means ± SEM, with n = 3 in each group (*P < 0.05, **P < 0.01)