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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Typical and atypical properties of peripheral nerve allografts enable novel strategies to repair segmental-loss injuries

Fig. 2

Strategies to use PNAs for regeneration of segmental PN defects. A Concept of localized immunosuppression, delivering Tregs that infiltrate graft, suppress the host immune response and support axonal extension. B Concept of axonal fusion across a PNA, restoring immediate electrical conductance. C Combination of axon fusion and localized immunosuppression that restores immediate conductance and protects the graft from the host immune response during critical periods and re-innervation based on axonal regeneration by outgrowth

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Journal of Neuroinflammation

ISSN: 1742-2094