Skip to main content
Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Gas6 induces inflammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer’s disease

Fig. 2

Gas6 overexpression worsens contextual fear conditioning performance in male APP/PS1 mice. A Schematic of contextual and cued fear conditioning task. B, C Freezing responses in each 30 s interval for male and female mice. N = 7–10 mice per group. Shaded areas represent mean ± SEM. Two-way ANOVA with Tukey’s multiple comparisons, *indicates APP-Gas6 group significantly differs from APP-control group for indicated 30 s time frame (p < 0.05). D, E Freezing responses in each 30 s interval for male and female mice during cued fear conditioning task in novel context. Vertical line indicates onset of conditioned tone. N = 7–10 mice per group. Upper and lower borders of shaded areas represent mean ± SEM

Back to article page