Fig. 1

Effects of EDA on CSDS-induced depressive and anxiety-like behaviors. A Schematic representation of the CSDS procedure and treatments in mice. B Heat maps of path tracing in the social interaction test after EDA administration. C Social interaction test. D Sucrose preference test. E Open field test. F Tail suspension test. G Forced swimming test. H, I Novel object recognition test. J Elevated plus maze test. All the data are expressed as mean ± SEM (n = 10 per group). **p < 0.01, ***p < 0.001 versus the CON + Vehicle group. ^#p < 0.05, ^##p < 0.01 versus the CSDS + Vehicle group