Fig. 2

Running exercise led to few DEGs in the hippocampus of APP/PS1 mice. a Volcano plot showing the DEGs in AD_Sed mice vs. WT_Sed mice. b Volcano plot showing the DEGs in AD_Run mice vs. AD_Sed mice. c Heatmap showing the top DEGs in WT_Sed, AD_Sed, and AD_Run mice. n = 3. Data are shown as |Log2 (fold change)|≥ 1, adjusted to p < 0.05