Fig. 2

Early intravenous administration of hAMSCs might improve ICH-induced neurobehavioral deficits during the subacute phase. A A protocol of neurobehavioral tests to optimize the timing of the hAMSC administration. The ICH-bearing mice were divided into four groups: D1-hAMSC group (n = 12), D3-hAMSC groups (n = 12), untreated ICH group (n = 11), and sham group (n = 12). The mice were then subject to the following neurobehavioral tests at Day 29 and later: open space swimming test (B), water maze learning test (C), and passive avoidance learning test (D). Data are plotted in mean ± SEM. P values are based on Tukey–Kramer test. *P < 0.05 and **P < 0.01 compared with the ICH group. ^#P < 0.05 and ^##P < 0.01 compared with the D3-hAMSC group