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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Choroid plexus-selective inactivation of adenosine A2A receptors protects against T cell infiltration and experimental autoimmune encephalomyelitis

Fig. 4

Knockdown of A2AR expression in the CP reduced the expression of CCL20. A Injection (i.p.) of KW6002 (dpi 8–14) reduced the expression of CCL20 on the CP at day 14 after immunization (n = 5/group). B, C Quantitative analysis of CCL20 in the CP in A (n = 5/group). Unpaired t test. D specific knock-down of A2AR in the CP inhibited the expression of CCL20 in CP at day 14 after immunization (n = 5/group). E–F Quantitative analysis of CCL20 in the CP in D (n = 5/group). Unpaired t test. **p < 0.01 and ***p < 0.001. “LV” = the lateral ventricle, and “3V” = the third ventricle

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Journal of Neuroinflammation

ISSN: 1742-2094