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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Evaluation of neuroprotective and immunomodulatory properties of mesenchymal stem cells in an ex vivo retinal explant model

Fig. 5

A Representative images of retinal explant cryosections cocultured with 1.104 MSCs for 7 days at DEV 0 and DEV 7, immunolabeled with GFAP (red) and DiO-labeled MSCs (green) at ×200 magnification (scale bar = 100 µm). B Quantification of GFAP immunoreactivity (expressed as Raw Integrated Density). n = 4–6 animals/group. Ordinary one-way ANOVA was performed. *P < 0.05, **P < 0.01. C RT-qPCR analysis of GFAP expression in retinal explants at DEV 0 and DEV 7. mRNA levels are presented after normalization with the housekeeping gene Rps18. n = 12 animals/group. Unpaired t-test was performed for unpaired comparisons. ****P < 0.0001

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