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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression

Fig. 5

Altered cytokine mRNA expression in ALS compared to HC MDMi Box-and-whisker plot of mRNA expression of pro-inflammatory cytokines (IL-6, IL-8, TNFα, IL-1β, IL-18) and alternatively activated cytokines (IL-10, TGFβ) in HC and ALS MDMi. HC and ALS MDMi were differentiated for 14 days prior to the collection of supernatant. Data were first tested for normality using Shapiro–Wilk test. Statistical analysis between two groups was performed using Mann Whitney U tests. Values are the mean ± SD (*P < 0.05, **P < 0.01)

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