Fig. 6
From: LXR agonist improves peripheral neuropathy and modifies PNS immune cells in aged mice
Activation of LXRs is associated with change in macrophage polarization. During oxygen consumption assay in the presence of oxLDL and with and without LXRs agonist GW3965 (A), LXRs activation significantly increased basal respiration (B), basal ECAR (C), maximal respiration (D), proton leak (E), and non-mitochondrial oxygen consumption F (n = 15 wells/group). All data are Mean ± SEM. *p < 0.05, ***p < 0.0005, ****p < 0.00005