Fig. 6

Quantification of sciatic nerve regeneration with SFI measurement. a SFI scores over the 8-week regeneration period following axotomy and coaptation. Dots represent SFI values at different time points, average ± SEM. N = 5 animals/group. *p < 0.05, **p < 0.01, ***p < 0.001 (vs. coapt. + vehicle, ANOVA with Fisher’s LSD post hoc). b, c Representative images of mouse footprints 3 days b and 56 days c after coaptation. Coapt. axotomy + coaptation, NTS normal toe spread, NPL normal paw length, ETS experimental toe spread, EPL experimental paw length