Fig. 5
From: Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage
Pathological changes in brain section and survival rates of infected mice. a Infected mice started to die on day 24 postinfection. b C57BL/6 mice have different brain pathological phenomena at different timepoints after infection with A. cantonensis, and they have more serious symptoms on day 21 postinfection (bar = 1 mm). c Comparison of pathological findings in the cerebral parenchyma of infected mice at different timepoints, including eosinophilic meningitis, encephalitis, congestion, hemorrhage, perivascular cuffing, larvae finding, choroid plexus inflammation, tissue necrosis. The scoring has increased significantly on days 14 and 21 postinfection (***P < 0.001, ***P < 0.001). d Comparison of encephalitis in the cerebral parenchyma of infected mice at different timepoints. The scoring has increased significantly on day 21 postinfection (***P < 0.001). e Scoring of presence of larvae in the cerebral parenchyma of infected mice. The data were analyzed by One-Way ANOVA