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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage

Fig. 7

Expression of cell death-related proteins in the brain of C57BL/6 mice infected with A. cantonensis. Western blotting was used to detect the expression of brain cell death-related proteins. a Expression of BDNF in the brain of infected mice showed significant manifestations on day 14 postinfection (*P < 0.05). b Apoptotic protein cleaved-caspase3 in the brain of infected mice increased significantly on day 21 postinfection (*P < 0.05). c, d There was no significant difference on the level of necroptotic protein RIP-3 and autophagy-related protein Beclin-1 before and after infection in mice. e Examples of the distribution and amounts of TUNEL positive cells by microscopic viewing (bar = 100 μm, 50 μm). f Mean fraction of TUNEL staining-positive cells to the number of available cells (*P < 0.05; ***P < 0.001). The data were analyzed by One-Way ANOVA

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