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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin αVβ5/AMPK signaling pathway after intracerebral hemorrhage in mice

Fig. 5

Effects of irisin on microglia/macrophage activation and neutrophil infiltration after ICH. A Representative images of immunofluorescence staining of Iba-1 (green), MPO (green), and IL-1β (green) in the perihematomal area at 24 h after ICH. BD Quantitative analyses of Iba-1, MPO, and IL-1β-positive cells in the perihematomal area at 24 h after ICH, n = 6 per group. EG Representative Western blot bands and quantitative analyses of Iba-1, MPO, and IL-1β protein levels in the ipsilateral hemisphere at 24 h after ICH. *p < 0.05, **p < 0.01, ***p < 0.001 vs. sham group; #p < 0.05, ##p < 0.01 vs. ICH + vehicle group. Error bars are represented as mean ± SD. One-way ANOVA, Tukey’s test, n = 6 per group, scale bar = 50 μm

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