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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Proteomic landscape subtype and clinical prognosis of patients with the cognitive impairment by Japanese encephalitis infection

Fig. 4

Changed proteins in CSF of patients in JE subgroups. A Biological process of JE2 vs. JE1 upregulated proteins based on GO analysis. B Protein interaction analysis of upregulated proteins evaluated using the STRING database. Negative regulation of endopeptidase activity, Immune response and complement activation proteins were the major upregulated proteins in JE2. C Biological process of JE2 vs. JE1 downregulated proteins based on GO analysis. D Neuron differentiation, axonogenesis, and neuron projection development, leukocyte and neutrophil degranulation, ATP generation, and platelet degranulation were the major upregulated proteins in JE2. E Heatmap of the differentially expressed proteins between subtypes JE1 and JE2

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