Fig. 3From: Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activationNLRP3 inflammasome activation is related to mechanical allodynia and frequent micturition in IC rats. A von Frey test showing that suprapubic mechanical withdrawal threshold of IC rats was significantly lower than normal rats, and MCC950 treatment significantly raised suprapubic mechanical withdrawal threshold of IC rats. n = 10 per group. B, C Urodynamic evaluation showing that IC rats exhibited significantly shorter micturition interval than normal rats, and MCC950 treatment significantly prolonged the micturition interval of IC rats. n = 6 per group. *P < 0.05Back to article page