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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation

Fig. 6

MSC-EVs restrain activation of glial cells and attenuate neuroinflammation in SDH of IC rats. A–C Western blot analysis showing that intrathecal injection of MSC-EVs significantly decreased expression levels of IBA-1 (microglia marker) and GFAP (astrocyte marker) in SDH of IC rats. D–F Western blot analysis showing that MSC-EV treatment significantly decreased expression levels of proinflammatory cytokine TNF-α and IL-6 in SDH of IC rats. n = 8 per group. *P < 0.05

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