Skip to main content
Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation

Fig. 8

MSC-EVs inhibit activity of TLR4/NF-κB signal pathway in SDH of IC rats. AC Western blot analysis showing that expression level of TLR4 and phosphorylation ratio of NF‐κB (p65) were significantly increased in SDH of IC rats compared with normal rats, and intrathecal injection of MSC-EVs significantly decreased expression level of TLR4 and phosphorylation ratio of NF‐κB (p65) in SDH of IC rats. n = 8 per group. *P < 0.05

Back to article page