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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway

Fig. 10

Intrathecal injection of SU16f promotes locomotor function recovery after SCI. A Timeline of the intrathecal injection and the behavioural assessment. B Locomotor function was evaluated by BMS at 0, 3, 7, 14, 21 and 28 dpi. ***P < 0.001 and ****P < 0.0001 vs. Control group by two-way ANOVA, n = 8 animals per group. C Representative images of footprint analysis in the Uninjured, Control and SU16f groups at 28 dpi. The front paws are shown in green dyes, and the hind paws are shown in red dyes. DF Quantification of the stride length, stride width and paw rotation at 28 dpi. *P < 0.05, ***P < 0.001 and ****P < 0.0001 by one-way ANOVA, n = 8 animals per group

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