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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway

Fig. 6

Intrathecal injection of SU16f reduces fibrotic scar after SCI. A–F Immunofluorescence staining of fibronectin (red) and PDGFRβ (green) in sagittal sections of the Control and SU16f groups at 28 dpi. G–L Immunofluorescence staining of laminin (red) and PDGFRβ (green) in sagittal sections of the Control and SU16f groups at 28 dpi. M–O Quantification of the percentage of PDGFRβ+ area, fibronectin+ area or laminin+ area in the area of the spinal cord segment spanning the injured core at 28 dpi. Asterisks indicate the injured core. Scale bars: 200 μm. ***P < 0.001 and ****P < 0.0001 by Student’s t test, n = 5 animals per group

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Journal of Neuroinflammation

ISSN: 1742-2094