Fig. 5

Expression of spleen homogenate of general pro-inflammatory mediators TNF-α, IL-1β, IL-12 and M-CSF mRNA’s, illustrated in deltaCts. Group size of control groups varies from n = 10 to 14, groups size of infected groups varies from n = 11 to 15. Parametric two-way ANOVA (factors: genetics and time-point) was conducted and continuous variables were tested with post hoc Student’s t-tests for M-CSF. Data represent mean ± SD. Non-parametric two-way ANOVA was conducted and continuous variables were tested with post hoc Mann–Whitney U tests for TNF-α, IL-1β, IL-12. For non-parametric ANOVAs, the ranked transformation of data was performed. Data represent median ± IQR. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001