Fig. 1

Effect of SUN11602 on behavioral impairments induced by MPTP. 7 days after MPTP injection mice showed a significant increase in behavioral deficits compared to the Sham group (A–D). Contrarily, SUN11602, at the two highest doses, considerably decreases “Time to turn” and “Time in closed arms” (A–D). Sham + SUN11602 administered groups were comparable to Sham + vehicle animals (A–D). Data are representative of at least three independent experiments. Values are means ± SEM. One-way ANOVA test. ***p < 0.001 vs Sham; ^#p < 0.05 vs MPTP; ^###p < 0.001 vs MPTP