Fig. 5
Expression of candidate neurologic genes is significantly dysregulated following low dose intracranial inoculation with ZIKV-DAK-MA. A qRT-PCR analysis of ZIKV RNA in the brains of 8-week-old C57BL/6 J mice at indicated day post-infection (dpi) following intracranial inoculation with ZIKV-DAK-MA (101 PFU). Values are reported in plaque forming unit-equivalents (PFUe) per hemisphere of brain tissue. n = 6–8 mice/group. B–O Expression profiles of 14 candidate genes assessed by qRT-PCR analysis on indicated days following intracranial ZIKV-DAK-MA infection. n = 6–8 mice/group. * p < 0.05, ** p < 0.01, *** p < 0.001. Bars represent group means