Fig. 2
From: An RNA-sequencing transcriptome of the rodent Schwann cell response to peripheral nerve injury
Purity of Schwann cell isolation. A Expression of typical Schwann cell, macrophage, fibroblast, and endothelial markers in whole nerve samples and purified Schwann cells at each day post-crush. B Expression of macrophage markers, CD45 and Cx3cr1, in purified Schwann cells as compared to whole nerve. Purified Schwann cells are almost completely devoid of myeloid markers. C Hierarchical clustering of all samples (top 2000 most variable genes; Linkage, average; ColumnPdistance, Spearman). D Schwann cell response to injury confirmed by expected upregulation of Sox10 and p75, and downregulation of myelin genes MBP and MPZ