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Table 2 Effects of high fat diet consumption on the metabolic hormones of WT or TLR4-mut mice

From: TLR4 mutation protects neurovascular function and cognitive decline in high-fat diet-fed mice

Metabolic hormones (pg/mL)

WT

TLR4-mut

ND

HFD

ND

HFD

Leptin

2323 ± 166

3302 ± 407

1868 ± 777

2535 ± 312

Resistin

4730 ± 499

8649 ± 145

3221 ± 499

4495 ± 517#

Glucagon

11.9 ± 0.2

7.3 ± 0.9

6.5 ± 1.0

5.1 ± 0.7

Ghrelin

6.9 ± 0.3

11.2 ± 1.9*

8.5 ± 0.5

8.20 ± 0.8

GIP

220 ± 19

430 ± 134*

211 ± 44

237 ± 45

  1. GIP glucose-dependent insulinotropic polypeptide. Values represent the mean ± SEM of 8–12 animals per group. *p < 0.05 vs. WT-ND and #p < 0.05 versus WT-HFD
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Journal of Neuroinflammation

ISSN: 1742-2094