Fig. 3
From: Association of inflammatory markers with cerebral small vessel disease in community-based population
Mendelian randomization association of genetic determinants of neutrophil count with the risk of CSVD phenotypes. Forest plot shows estimates for the effects of neutrophil count related genetic variants on risk of cerebral small vessel disease phenotypes including white matter hyperintensities volume, lacunar stroke, small vessel stroke and cerebral microbleeds. The results are derived from the random-effects IVW (inverse-variance weighted) Mendelian randomization analysis and presented as odds ratios (95% confidence interval [CI]). Red rows correspond to statistically significant association estimates at a P_FDR (false discovery rate-adjusted p value) < 0.05. CSVD cerebral small vessel disease; SNPs single nucleotide polymorphisms, ORs odds ratios; WMH white matter hyperintensities, CMBs cerebral microbleeds