Fig. 1From: Network alterations underlying anxiety symptoms in early multiple sclerosisStudy design and work flow. After fulfilling the inclusion criteria (red dashed line box), 92 early multiple sclerosis patients were included for the cortical thickness correlation analysis with HADS-A scores (anxiety symptoms) to generate an anxiety-related atrophy map. Next, atrophy network mapping was applied to project this atrophy map onto a normative functional brain network (n = 1000). As a result, we were able to determine brain regions functionally connected to the atrophied locationBack to article page