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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Agomelatine rescues lipopolysaccharide-induced neural injury and depression-like behaviors via suppression of the Gαi-2-PKA-ASK1 signaling pathway

Fig. 1

Agomelatine reverses LPS-induced depression-like behaviors in rats. A Schematic diagram of experimental design. B Agomelatine reversed the decreases in percent of sucrose consumption in the SPT and C increased immobility times in the FST in the LPS-induced rat model of depression. D Amount of time in the open arms and E number of entries into the open arms in the EPM test. N = 18 per group, *P < 0.05, LPS vs Control group; #P < 0.05, LPS vs LPS + AGO (AGO, Agomelatine). The data are presented as means ± SEMs

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Journal of Neuroinflammation

ISSN: 1742-2094