Fig. 1

Distribution of CXCL12, IL-8, CX3CL1 and CCL15 between HC and PD participants and ROC curve analysis. a–d Levels of CXCL12, IL-8, CX3CL1 and CCL15 in plasma between two groups measured by MSD assay. e ROC curve between two groups. The blue line is the ROC curve for CX3CL1, and the AUC is 0.63. The green line is the ROC curve for CXCL12, and the AUC is 0.83. The red line is the ROC curve for IL-8, and the AUC is 0.85. The purple line is the ROC curve for the integrative model, and the AUC is 0.89. *p < 0.05, ****p < 0.0001