|
Biomarkers
|
Discovery
|
Validation
|
Combined-analysis
|
|---|
|
OR (95% CI)
|
p value
|
OR (95% CI)
|
p value
|
OR (95% CI)
|
p value
|
|---|
|
CXCL12
|
9 (4.3–18.7)
|
4.5 × 10–9
|
2.3 (1.1–4.6)
|
0.02
|
3.8 (2.4–6.2)
|
4.7 × 10–8
|
|
CX3CL1
|
3.1 (1.6–6.0)
|
7.8 × 10–4
|
2.8 (1.4–5.4)
|
2.4 × 10–3
|
2.9 (1.7–4.9)
|
1.5 × 10–4
|
|
IL-8
|
19.0 (8.2–44.3)
|
7.6 × 10–12
|
57.0 (18.5–174.7)
|
1.9 × 10–12
|
26.9 (12.9–56.4)
|
2.3 × 10–18
|
|
CCL15
|
0.3 (0.2–0.7)
|
4.7 × 10–3
|
0.5 (0.2–1.0)
|
0.045
|
0.4 (0.3–0.7)
|
0.001
|
- p value was adjusted for age, gender and site under logistic regression analysis model
- The bold emphasis in the table means p < 0.05
- OR odds ratio, 95% CI 95% confidence interval
