Skip to main content

Table 4 Longitudinal assessments in follow-up early PD patients

From: Parkinson's disease peripheral immune biomarker profile: a multicentre, cross-sectional and longitudinal study

Characteristics

Baseline (n = 39)

Follow-up (n = 39)

p value

Age (years)

68.5 ± 7.7

/

/

Sex, N

  

/

 Male

26

/

/

 Female

13

/

/

Disease duration (years)

   

 UPDRS I

3.3 ± 2.7

6.3 ± 4.1

 < 0.001***

 UPDRS II

9.9 ± 4.3

12.1 ± 4.8

0.041

 UPDRS III

18.8 ± 8.5

26.9 ± 9.6

 < 0.001***

 NMSQ

8.2 ± 4.1

10.6 ± 4.3

0.014

 SS-16

6.7 ± 3.3

5.6 ± 2.5

0.099

 RBDSQ

5.0 ± 4.3

5.7 ± 3.6

0.45

 HAMD-17

5.7 ± 4.4

6.1 ± 4.7

0.71

 SCOPA-AUT

13.8 ± 9.6

16.1 ± 8.5

0.27

 MMSE

27.2 ± 3.5

27.5 ± 2.8

0.60

 MoCA

23.2 ± 5.2

22.8 ± 5.4

0.76

  1. Data are expressed as mean and standard deviation (SD), as appropriate
  2. The bold emphasis in the table means p < 0.05
  3. NMSQ the Non-Motor Symptom Questionnaire, SCOPA-AUT Scale for Outcomes in PD-Autonomic, SS-16 Sniffin’ Sticks 16-item test, HAMD-17 17-item Hamilton Depression Rating Scale, MMSE Mini-Mental State Examination, MoCA Montreal Cognitive Assessment, iRBD idiopathic REM sleep behavior disorder