Fig. 4From: Prehabilitative resistance exercise reduces neuroinflammation and improves mitochondrial health in aged mice with perioperative neurocognitive disordersResistance training inhibited inflammatory responses in the brain and peripheral organs of aged mice following surgery. a Relative mRNA levels of the inflammatory cytokines IL-1β, TNF-α, MCP-1 and the anti-inflammatory IL-10 in the hippocampus, muscle and liver after RE training. Data analyzed by unpaired Student’s t-test, n = 8. Data presented as mean ± SEM. *p < 0.05, **p < 0.01. b Relative mRNA levels of IL-1β, TNF-α, MCP-1 and IL-10 in the hippocampus at 24 h after surgery. Significant reduction in MCP-1 expression was observed in RE + Lap group. c Protein levels of IL-1β, TNF-α, MCP-1 and IL-10 in the hippocampus at 14 days after surgery. Significant reduction in MCP-1 expression was also observed in RE + Lap group. Data analyzed by one-way ANOVA with Tukey post hoc test, n = 8. Data presented as mean ± SEM. *p < 0.05Back to article page