Fig. 6From: Prehabilitative resistance exercise reduces neuroinflammation and improves mitochondrial health in aged mice with perioperative neurocognitive disordersResistance training modulated different myokines and intracellular signal pathways in the brain following surgery. a–c Relative mRNA levels of FGF-21, PGC-1α and IL-6 in the hippocampus, muscle and liver. d–f Representative blots and quantitative analysis of key proteins in intracellular signal transduction in the hippocampus on postoperative day 1 and (g–i) day 14, respectively. The intensity of band of BDNF, Akt, GSK3β, Bax and Bcl-2 was normalized to GAPDH. Data were analyzed by two-way ANOVA, followed by Tukey multiple comparisons test, n = 6. Data presented as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001Back to article page