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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome

Fig. 10

SR9009 reversed the phenotypic polarization of microglia in the SN of MPTP-induced mice. A Representative double-immunofluorescent staining of IBA1 (green) and iNOS (red) in the SN. Scale bar, 50 μm. D Representative double-immunofluorescent staining of IBA1 (green) and iNOS (Arg-1) in the SN. Scale bar, 50 μm. The real-time PCR results of iNOS (B), Arg-1 (C), TNF-α (E) and IL-6 (F) in the SN. n = 3–4 for each group. Data were presented as mean ± SEM. (*p < 0.05, **p < 0.01, or ***p < 0.001 by One-way ANOVA test)

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Journal of Neuroinflammation

ISSN: 1742-2094