Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome

Fig. 6

SR9009 ameliorates behavioral impairments in MPTP-induced Mice. A Schematic representation of SR9009 intervention therapy. SR9009 was injected intraperitoneally (100 mg/kg/day) for 7 consecutive days prior to MPTP administration and was continued along with MPTP treatment. Behavioral tests began the day after completing 14 days of SR9009 treatment, and mice were killed after behavioral test (day 18). B Time spent in climbing of the pole test. C The time taken to cross the balance beam. D Latency to fall of the rotarod test. E Body-weight changes over time. n = 10 for each group. Data were presented as mean ± SEM. (*p < 0.05, **p < 0.01, or ****p < 0.0001 by One-way ANOVA test)

Back to article page