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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome

Fig. 7

SR9009 protects against dopaminergic neurons degeneration in MPTP-induced mice. The representative immunohistochemical staining of TH (A) and the OD of TH staining (B) in the striatum. Scale bar, 1 mm. Representative western blot bands (C) and the statistical graph (D) of TH in the striatum. The representative immunohistochemical staining of TH (E) and the number of TH positive neurons (F) in the SN. Scale bar, 500 μm. Representative western blot bands (G) and the statistical graph (H) of TH in the SN. I The representative Nissl staining for neurons in the SN. Scale bars, 200 μm for the top row and 50 μm for the bottom row. The TH protein level was normalized to β-actin. n = 3–4 for each group. Data were presented as mean ± SEM. (*p < 0.05, **p < 0.01, or ***p < 0.001 by one-way ANOVA test)

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