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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: The circadian clock protein Rev-erbα provides neuroprotection and attenuates neuroinflammation against Parkinson’s disease via the microglial NLRP3 inflammasome

Fig. 8

SR9009 inhibits microgliosis and astrocytosis in the SN of MPTP-induced mice. The representative immunohistochemistry staining (A) and the statistical graph (B) of IBA1 in the SN. Scale bars, 250 μm for the top row and 50 μm for the bottom row. The representative immunohistochemistry staining (C) and the statistical graph (D) of GFAP in the SN. Scale bars, 500 μm for the top row and 100 μm for the bottom row. Representative western blot bands (E) and the statistical graph (F, G) of IBA1 and GFAP in the SN. The protein levels were normalized to β-actin. n = 3–4 for each group. Data were presented as mean ± SEM. (*p < 0.05, **p < 0.01, or ***p < 0.001 by one-way ANOVA test)

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