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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Persistent cortical and white matter inflammation after therapeutic hypothermia for ischemia in near-term fetal sheep

Fig. 2

Cortical neuronal area and cortical lesions. A Graph showing NeuN area measurements for the cortex of the sagittal (SC), first parasagittal (PSC1) and second parasagittal gyri (PSC2). Representative NeuN whole section images for B sham control (n = 8), E ischemia-normothermia (n = 8) and H ischemia-hypothermia (n = 8). Representative GFAP images in the cortex taken from area denoted by the box for C sham control showing no lesions, F ischemia-normothermia showing lesions and I ischemia-hypothermia showing no lesions. Representative Iba1 images in the cortex for D sham control showing no lesions, G ischemia-normothermia showing lesions and J ischemia-hypothermia showing no lesions. Arrows indicate lesions. *(p < 0.05) vs. sham control, ^(p < 0.05) vs. ischemia-normothermia, repeated measures ANOVA and LSD post hoc test. Scale bar for F = 5 mm (NeuN), scale bar for J = 200 µm (GFAP and Iba1)

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Journal of Neuroinflammation

ISSN: 1742-2094