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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Persistent cortical and white matter inflammation after therapeutic hypothermia for ischemia in near-term fetal sheep

Fig. 3

White matter MBP area and area fraction measurements and white matter lesions. A Graph showing MBP area measurements and B MBP area fraction for the intragyral white matter of the sagittal gyrus (SWM) and the first parasagittal gyrus (IGWM1) and second parasagittal gyrus (IGWM2). Representative MBP whole section images for C sham control (n = 8), F ischemia-normothermia (n = 8) and I ischemia-hypothermia (n = 8). Representative images for D intact MBP in sham control, E extensive diffuse MBP loss in ischemia-normothermia, G small lesions in ischemia-normothermia, H large lesions in ischemia-normothermia, J intact MBP in ischemia-hypothermia and K localized diffuse MBP loss in ischemia-hypothermia. Arrows with tails indicate lesions. Arrow heads without tails indicate areas of localized diffuse MBP loss. *(p < 0.05) vs. sham control, ^(p < 0.05) vs. ischemia-normothermia, repeated measures ANOVA and LSD post hoc test. Scale bar for I = 5 mm, scale bar for K = 500 µm

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