Fig. 2From: Using zebrafish to understand reciprocal interactions between the nervous and immune systems and the microbial worldExamples of pathological interactions involving CNS invasion. Pathogens (including but not limited to those listed) may infect immune cells or directly invade neurons or the CNS in zebrafish. Infected immune cells in the periphery may either elicit peripheral nerve damage or cross the blood–brain barrier and invade the CNS, causing neuroinflammation and subsequent neuronal damage. Infection can result in behavioral changes with some similarities to mammalsBack to article page