Skip to main content
Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Effect of rottlerin on astrocyte phenotype polarization after trimethyltin insult in the dentate gyrus of mice

Fig. 6

Experimental schedule and the effect of rottlerin on the expression of Iba-1 in the dentate gyrus of mice 6 days after TMT treatment. A Effect of rottlerin on Iba-1 immunoreactivity. B Effect of rottlerin on the morphology of Iba-1-positive cells in the dentate gyrus of TMT-treated mice. Square boxes in A and B indicate the region of interest (ROI) for quantification. Veh, Vehicle. Sal, Saline. Rot, Rottlerin. Each value is the mean ± S.E.M. of 4 (Vehicle + Saline and Rottlerin + Saline) or 5 (Vehicle + TMT and Rottlerin + TMT) mice. *P < 0.05, **P < 0.01 vs. corresponding Saline; ##P < 0.01 vs. Vehicle + Saline [two-way ANOVA followed by Fisher’s LSD pairwise comparisons test A or unpaired t-test (B)]. Scale bar = 200 µm

Back to article page