Fig. 7

Effect of rottlerin on the mRNA expression of astrocyte phenotype markers in the dentate gyrus of mice 6 days after TMT treatment. C3, CFB, GGTA1, and MX1 are A1 phenotype markers. S100A10, EMP1, and CD109 are A2 phenotype markers. Veh, Vehicle. Sal, Saline. Rot, Rottlerin. Each value is the mean ± S.E.M. of 6 (Vehicle + Saline, Rottlerin + Saline, Vehicle + TMT, and Rottlerin + TMT) mice. ^**P < 0.01 vs. corresponding Saline; ^##P < 0.01 vs. Vehicle + Saline (two-way ANOVA followed by Fisher’s LSD pairwise comparisons test)