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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Activating cGAS–STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis

Fig. 4

Effect of RU.521 on cortical neuronal injury and motor function after CVST. A Typical photomicrographs of TUNEL staining and C quantitative analyses at the indicated groups. n = 6 per group. B Representative pictures of FJC staining and D quantitative analyses in diverse groups. n = 6 per group. E Motor function was evaluated by rotarod test at pre-surgery and 1 d, 3 d, 5 d, 7 d, 10 d and 14 d post-operation. The number of mice in the Sham + vehicle group, CVST + vehicle group, and CVST + RU.521 group was 6, 8, and 9, respectively. **P < 0.01, *P < 0.05. Scale bar = 50 μm

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Journal of Neuroinflammation

ISSN: 1742-2094