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Table 1 The most significantly upregulated mRNAs in hBMECs upon infection

From: SARS-CoV-2 productively infects human brain microvascular endothelial cells

Gene symbol

Ensembl gene ID

log2(fold change)

p value

q value

PRRC2A

ENSG00000204469

21.97584681

1.86E−08

1.53E−07

PTDSS2

ENSG00000174915

21.30706691

5.01E−08

3.88E−07

SAA2

ENSG00000134339

10.07835285

3.79E−17

6.57E−16

SAA1

ENSG00000173432

9.932668453

5.99E−17

1.02E−15

LCN2

ENSG00000148346

9.826441157

1.49E−51

8.29E−50

SULT1A4

ENSG00000213648

9.478170754

0.015280772

0.042089886

SFT2D3

ENSG00000173349

8.882246082

5.53E−13

7.05E−12

CHI3L1

ENSG00000133048

8.853778776

1.20E−41

5.21E−40

CFB

ENSG00000243649

8.432931778

6.22E−12

7.35E−11

CCL20

ENSG00000115009

8.275035624

4.64E−125

7.85E−123

CSF2

ENSG00000164400

8.201980672

3.01E−15

4.57E−14

PI3

ENSG00000124102

8.089107263

8.07E−11

8.64E−10

TNF

ENSG00000232810

8.020602424

1.11E−10

1.17E−09

CHI3L2

ENSG00000064886

7.836029091

3.94E−10

3.88E−09

CSF3

ENSG00000108342

7.776493262

7.93E−20

1.59E−18

C15orf48

ENSG00000166920

7.250651063

0

0

SAA2-SAA4

ENSG00000255071

7.18957744

3.05E−08

2.44E−07

PDZK1IP1

ENSG00000162366

7.168359056

2.26E−81

2.17E−79

PTX3

ENSG00000163661

6.916996585

1.80E−15

2.77E−14

CXCL2

ENSG00000081041

6.754935681

8.15E−113

1.19E−110

IL1B

ENSG00000125538

6.695314953

3.74E−27

1.08E−25

CXCL8

ENSG00000169429

6.669732672

3.53E−292

1.71E−289

LTB

ENSG00000227507

6.542726279

2.40E−07

1.70E−06

IL3RA

ENSG00000185291

6.474107802

1.86E−06

1.14E−05

CA9

ENSG00000107159

6.440743779

2.39E−06

1.45E−05

CXCL1

ENSG00000163739

6.365756137

0

0

SMG1

ENSG00000157106

6.227596608

9.18E−06

5.04E−05

ATF6B

ENSG00000213676

6.220025614

0.000252727

0.0010654

CCL2

ENSG00000108691

6.206816673

2.96E−61

2.04E−59

G0S2

ENSG00000123689

6.171508146

1.04E−05

5.69E−05

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Journal of Neuroinflammation

ISSN: 1742-2094